Repair
TB-500
Choose TB-500 10mg in Peptide Pen format with third-party testing and a batch-specific COA. Research quality should be documented, not assumed. Purita makes the key quality details easy to verify before you order.
€79.90 · 10mg
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Product information
What it is TB-500 is a seven-amino-acid synthetic peptide with the sequence Ac-LKKTETQ. It matches residues 17-23 of thymosin beta-4 (Tβ4), a much larger 43-amino-acid peptide. That difference is easy to miss, since the two names are often used together. The shorter sequence is a fragment of Tβ4, not another name for the full-length peptide. It also makes a difference when reading the research. There is a substantial body of published work on thymosin beta-4, but far less on the isolated fragment itself. How it works and what the research shows The seven-amino-acid sequence comes from a part of Tβ4 linked to actin. Actin is a major component of the cell's internal structure and is also involved when cells change shape or move. Research on this region has therefore looked at processes such as actin dynamics and cell migration. Evidence for the isolated fragment, however, is still limited. Full-length thymosin beta-4 has been studied much more extensively. Animal and laboratory research has examined its role in angiogenesis, cell migration and tissue repair. Other studies have looked at cardiac and neurological injury models, including oligodendrocyte differentiation and remyelination. Tissue-repair research also includes peptides with quite different experimental backgrounds. BPC-157, for example, has been investigated in animal models involving tendon, ligament and other tissue