Metabolic
CJC-1295 + Ipamorelin Blend
Some research demands a higher concentration without compromising consistency. Choose the CJC-1295 5mg + Ipamorelin 5mg Blend with verified 99%+ purity, double-tested quality and complete batch documentation from Purita Peptides.
€89.90 · 5mg + 5mg
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Product information
What it is CJC-1295 without DAC is a synthetic GHRH analogue that stimulates the pituitary to release growth hormone in short, controlled pulses. Another name you may come across is Modified GRF (1-29), or simply Mod GRF 1-29. Without DAC, its activity is relatively short-lived. That makes the timing of the GH signal part of what researchers can study. Ipamorelin gets to GH release by a different route. It activates the ghrelin receptor GHS-R1a, rather than the GHRH receptor used by CJC-1295. Combining them puts both signals into the same experimental model. How it works and what the research shows The basic idea behind the blend is fairly simple. CJC-1295 sends a GHRH signal to the pituitary; ipamorelin provides a second signal through the ghrelin receptor. Both can lead to GH release, but they start at different receptors. Ipamorelin is quite selective for GH release compared with some of the earlier secretagogues studied before it. Experiments found much smaller ACTH and cortisol responses than with less selective compounds. This difference is one reason it has been used in research where changes outside the GH pathway could make the results harder to interpret. Then there is IGF-1. GH can increase its production, so experiments involving GH signalling often look further down this axis as well. Human trials of CJC-1295 did find increases in GH and IGF-1, but those trials wer